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- <text id=93TT1178>
- <title>
- Mar. 15, 1993: Genetic Revelation
- </title>
- <history>
- TIME--The Weekly Newsmagazine--1993
- Mar. 15, 1993 In the Name of God
- </history>
- <article>
- <source>Time Magazine</source>
- <hdr>
- THE WEEK
- HEALTH & SCIENCE, Page 22
- Genetic Revelations
- </hdr>
- <body>
- <p>Researchers discover the gene that causes Lou Gehrig's disease
- </p>
- <p> Pages are being added to the book of genetics at an
- accelerating pace these days. Researchers announced that they
- have identified a defective gene that appears to cause
- amyotrophic lateral sclerosis, better known as Lou Gehrig's
- disease. About 30,000 Americans suffer from the disorder, which
- causes degeneration of the nerves that carry signals to muscles.
- The trouble in some cases, scientists reported in Nature,
- apparently lies in the gene that directs production of an enzyme
- that mops up free radicals. These substances are metabolism's
- nasty residue.
- </p>
- <p> In the same journal, scientists revealed that multiple
- sclerosis, the crippling nervous-system disease, may be linked
- to white blood cells with a specific genetic rearrangement.
- These white cells seem to destroy the sheath that surrounds
- nerves and protects their ability to conduct messages.
- </p>
- <p> As researchers are finding out how genes cause illness,
- they are also working on genetic cures. A federal panel approved
- a new trial of an experimental gene therapy for brain cancer.
- Doctors take a gene from the herpes virus and insert it into
- tumor cells. They then zap the cells with an antiviral drug that
- attacks the herpes gene--and thus the tumor.
- </p>
-
- </body>
- </article>
- </text>
-
-